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Paolo Chieffi Selected Research

Seminoma

11/2021GPR30: A new potential therapeutic target in human testicular germ cell tumors.
4/2020HMGA1-Regulating microRNAs Let-7a and miR-26a are Downregulated in Human Seminomas.
5/2019An up-date on novel molecular targets in testicular germ cell tumors subtypes.
1/2019New Anti-Cancer Strategies in Testicular Germ Cell Tumors.
2/2018Recent Advances in New Discovered Molecular Targets in Testicular Germ Cell Tumors.
5/2016New perspective on molecular markers as promising therapeutic targets in germ cell tumors.
6/2015High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness.
8/2014An up-date on newly discovered immunohistochemical biomarkers for the diagnosis of human testicular germ cell tumors.
1/2014Recent advances in molecular and cell biology of testicular germ-cell tumors.
8/2013Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: an overview.
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Paolo Chieffi Research Topics

Disease

24Neoplasms (Cancer)
11/2021 - 01/2002
16Seminoma
11/2021 - 03/2005
10Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
01/2021 - 03/2005
6Teratoma (Teratoid Tumor)
11/2017 - 03/2005
5Carcinogenesis
11/2021 - 09/2006
3Embryonal Carcinoma
03/2011 - 03/2005
3Carcinoma (Carcinomatosis)
11/2009 - 02/2005
3Prostatic Neoplasms (Prostate Cancer)
04/2009 - 01/2002
2Carcinoma in Situ
11/2021 - 06/2015
2Neoplasm Metastasis (Metastasis)
01/2021 - 10/2006
1Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2022
1Testicular Neoplasms (Testicular Cancer)
01/2021
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2020
1Testicular Germ Cell Tumor
01/2019
1Chromosome Duplication
05/2018
1Ataxia (Dyssynergia)
09/2013
1Anaplastic Thyroid Carcinoma
02/2011
1Polyploidy
02/2011
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2010
1Multiple Sclerosis
12/2010
1Aneuploidy (Aneuploid)
11/2009
1Genomic Instability
11/2009
1Ataxia Telangiectasia (Louis Bar Syndrome)
11/2008
1Adenoma (Adenomas)
09/2007
1Pituitary Neoplasms (Pituitary Adenoma)
09/2007
1Encephalomyelitis (Myeloencephalitis)
02/2006
1Disease Progression
02/2006
1Necrosis
01/2002

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2002
7Phosphotransferases (Kinase)IBA
03/2014 - 07/2007
5Biomarkers (Surrogate Marker)IBA
01/2021 - 04/2009
5MicroRNAs (MicroRNA)IBA
01/2021 - 11/2017
3Estrogens (Estrogen)FDA Link
11/2021 - 12/2012
3Hormones (Hormone)IBA
11/2021 - 12/2010
3Aurora KinasesIBA
01/2019 - 02/2005
2GTP-Binding Proteins (G-Protein)IBA
11/2021 - 06/2015
2Estrogen ReceptorsIBA
11/2021 - 06/2015
2Mitogen-Activated Protein Kinase 3IBA
11/2021 - 01/2002
2RNA (Ribonucleic Acid)IBA
01/2021 - 01/2020
2HMGA ProteinsIBA
01/2021 - 04/2020
2Messenger RNA (mRNA)IBA
04/2020 - 03/2005
2Tumor Biomarkers (Tumor Markers)IBA
11/2017 - 01/2009
2Threonine (L-Threonine)FDA Link
08/2013 - 07/2007
2Serine (L-Serine)FDA Link
08/2013 - 07/2007
2Tyrosine (L-Tyrosine)FDA Link
08/2013 - 07/2007
2Pharmaceutical PreparationsIBA
01/2012 - 02/2011
2Peptides (Polypeptides)IBA
12/2010 - 02/2006
2LeptinIBA
12/2010 - 02/2006
2Focal Adhesion Kinase 2IBA
10/2006 - 01/2002
1Biological ProductsIBA
01/2021
1Protein SIBA
04/2020
1pembrolizumabIBA
01/2019
1Immune Checkpoint InhibitorsIBA
01/2019
1NivolumabIBA
01/2019
1Monoclonal AntibodiesIBA
01/2019
1Brentuximab VedotinIBA
01/2019
1claudin 6IBA
01/2019
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
05/2018
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
11/2017
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
11/2017
1human AFP proteinIBA
11/2017
1Estrogen Receptor betaIBA
06/2015
1RNA Splicing FactorsIBA
03/2014
1PhosphoproteinsIBA
09/2013
1Humanized Monoclonal AntibodiesIBA
08/2013
1PlatinumIBA
08/2013
1Transcription Factors (Transcription Factor)IBA
03/2013
1Zoledronic Acid (Zometa)FDA Link
01/2012
1Liposomes (Liposome)IBA
01/2012
12- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphateIBA
02/2011
1Aurora Kinase BIBA
02/2011
1Glycoproteins (Glycoprotein)IBA
12/2010
1AntioxidantsIBA
10/2010
1ResveratrolIBA
10/2010
1Chromatin Assembly Factor-1IBA
04/2009
1Cisplatin (Platino)FDA LinkGeneric
01/2009
1OligonucleotidesIBA
09/2007
1ProlactinIBA
09/2007
1Angiogenesis InhibitorsIBA
07/2007
1Endocrine-Gland-Derived Vascular Endothelial Growth Factor (Vascular Endothelial Growth Factor, Endocrine Gland Derived)IBA
09/2006
1Histones (Histone)IBA
02/2006
1CytokinesIBA
02/2006
1mouse leptin receptorIBA
02/2006
1PTEN Phosphohydrolase (PTEN Phosphatase)IBA
03/2005
1lysophosphatidic acidIBA
01/2002

Therapy/Procedure

9Therapeutics
05/2019 - 01/2009
3Drug Therapy (Chemotherapy)
02/2017 - 02/2011
1Combination Drug Therapy (Combination Chemotherapy)
08/2013
1Prostatectomy (Retropubic Prostatectomy)
03/2002